| Standard Scoring | ||
| 1 | Saquon Barkley | PIT |
| 2 | Josh Jacobs | @ SEA |
| 3 | Joe Mixon | MIA |
| 4 | Bijan Robinson | @ LV |
| 5 | Derrick Henry | @ NYG |
| 6 | Jahmyr Gibbs | BUF |
| 7 | Chase Brown | @ TEN |
| 8 | Kyren Williams | @ SF |
| 9 | David Montgomery | BUF |
| 10 | De'Von Achane | @ HOU |
| 11 | James Conner | NE |
| 12 | Zach Charbonnet | GB |
| 13 | Chuba Hubbard | DAL |
| 14 | Tony Pollard | CIN |
| 15 | Rachaad White | @ LAC |
| 16 | Brian Robinson | @ NO |
| 17 | Aaron Jones | CHI |
| 18 | James Cook | @ DET |
| 19 | Alvin Kamara | WAS |
| 20 | Tyrone Tracy | BAL |
| 21 | Jonathan Taylor | @ DEN |
| 22 | Najee Harris | @ PHI |
| 23 | Patrick Taylor | LAR |
| 24 | Isiah Pacheco | @ CLE |
| 25 | Rico Dowdle | @ CAR |
| 26 | D'Andre Swift | @ MIN |
| 27 | Rhamondre Stevenson | @ ARI |
| 28 | Nick Chubb | KC |
| 29 | Braelon Allen | @ JAC |
| 30 | Javonte Williams | IND |
| 31 | Sincere McCormick | ATL |
| 32 | Cartavious Bigsby | NYJ |
| 33 | Jaylen Warren | @ PHI |
| 34 | Gus Edwards | TB |
| 35 | Isaiah Davis | @ JAC |
| 36 | Travis Etienne | NYJ |
| 37 | Tyler Allgeier | @ LV |
| 38 | Jerome Ford | KC |
| 39 | Sean Tucker | @ LAC |
| 40 | Tyjae Spears | CIN |
| 41 | Kimani Vidal | TB |
| 42 | Ameer Abdullah | ATL |
| 43 | Kareem Hunt | @ CLE |
| 44 | Jaleel McLaughlin | IND |
| 45 | Jaylen Wright | @ HOU |
| 46 | Ray Davis | @ DET |
| 47 | Cam Akers | CHI |
| 48 | Emanuel Wilson | @ SEA |
| 49 | Ke'Shawn Vaughn | LAR |
| 50 | Trey Benson | NE |
| PPR Scoring | ||
| 1 | Saquon Barkley | PIT |
| 2 | Josh Jacobs | @ SEA |
| 3 | Joe Mixon | MIA |
| 4 | Bijan Robinson | @ LV |
| 5 | Chase Brown | @ TEN |
| 6 | Jahmyr Gibbs | BUF |
| 7 | De'Von Achane | @ HOU |
| 8 | David Montgomery | BUF |
| 9 | Derrick Henry | @ NYG |
| 10 | James Conner | NE |
| 11 | Kyren Williams | @ SF |
| 12 | Zach Charbonnet | GB |
| 13 | Rachaad White | @ LAC |
| 14 | Chuba Hubbard | DAL |
| 15 | Alvin Kamara | WAS |
| 16 | Tony Pollard | CIN |
| 17 | Aaron Jones | CHI |
| 18 | Brian Robinson | @ NO |
| 19 | Tyrone Tracy | BAL |
| 20 | James Cook | @ DET |
| 21 | Jonathan Taylor | @ DEN |
| 22 | Rico Dowdle | @ CAR |
| 23 | Najee Harris | @ PHI |
| 24 | Patrick Taylor | LAR |
| 25 | Isiah Pacheco | @ CLE |
| 26 | D'Andre Swift | @ MIN |
| 27 | Rhamondre Stevenson | @ ARI |
| 28 | Jaylen Warren | @ PHI |
| 29 | Javonte Williams | IND |
| 30 | Nick Chubb | KC |
| 31 | Braelon Allen | @ JAC |
| 32 | Sincere McCormick | ATL |
| 33 | Travis Etienne | NYJ |
| 34 | Isaiah Davis | @ JAC |
| 35 | Cartavious Bigsby | NYJ |
| 36 | Jerome Ford | KC |
| 37 | Ameer Abdullah | ATL |
| 38 | Gus Edwards | TB |
| 39 | Sean Tucker | @ LAC |
| 40 | Tyjae Spears | CIN |
| 41 | Tyler Allgeier | @ LV |
| 42 | Kimani Vidal | TB |
| 43 | Kareem Hunt | @ CLE |
| 44 | Jaleel McLaughlin | IND |
| 45 | Justice Hill | @ NYG |
| 46 | Jaylen Wright | @ HOU |
| 47 | Ray Davis | @ DET |
| 48 | Samaje Perine | @ CLE |
| 49 | Cam Akers | CHI |
| 50 | Emanuel Wilson | @ SEA |